⚡️ GPT-5 enters a wet lab and boosts DNA cloning efficiency by 79×

OpenAI partnered with Red Queen Bio to test GPT-5 inside a real biological laboratory. The model was embedded in a closed-loop wet lab workflow, not a simulation.

How the experiment worked
• GPT-5 proposed hypotheses and step-by-step lab protocols
• Human researchers or lab robots executed the instructions exactly
• Experimental results were fed back to the model
• GPT-5 analyzed failures and successes, then iterated
• The loop repeated over multiple rounds

The task
• Optimize Gibson Assembly, a standard DNA cloning techniqu